2026 MRFF Million Minds Mental Health Research Mission · Stream 1 Incubator · Topic C · In development

FAMILY

Safe family-aware early identification and service planning for youth depression

By the end of two years, FAMILY will deliver Australia's first co-designed, partner-tested framework for using family context safely in the early identification and care of youth depression — ready for implementation testing in adolescent primary care and youth mental-health services. It is built on 24 years of national intergenerational evidence and a pathway into Australia's national linked data, and shaped end-to-end by young people, carers and clinicians.

We are finalising the investigator team and partner letters by early August 2026, ahead of the MRFF submission closing 16 September 2026. If FAMILY fits your organisation, now is the moment.

Get in touch One-pager ↗ Project spine ↗ Pilot study ↗ 2026 draft ↗

The project spine is an early four-page document for discussion. The 2026 proposal is a working draft and will continue to change as the MRFF submission develops.

24 yrs of national intergenerational panel data underpinning the evidence base 43,817 parent-child pairs in the proof-of-concept sample
23 HILDA waves underpinning the marker-development analysis
0–25 age range of young people in scope
16 Sep 2026 MRFF submission deadline; partners confirmed by early August

The problem

Services lack an evidence-based, safe way to use family context in youth depression care.

Young people are embedded in families and households. Parental depression, household shocks, family resources, service contact, economic stress, housing instability, relationship transitions and protective supports can shape vulnerability, recognition, access to care, persistence and recovery. Yet most evidence and service responses still start and end with the individual young person.

The practical gap is not simply that we need a larger dataset. It is that services and policy lack an evidence-based, youth-safe way to use family context in early identification and service planning. FAMILY asks which family-context markers are evidence-supported, administratively measurable, clinically useful, acceptable to young people and carers, and safe enough to inform support.

Preliminary intergenerational HILDA work uses 43,817 parent-child pairs across 23 waves. It shows significant mental-health gradients for both mothers and fathers, with maternal gradients roughly twice paternal ones. These are observational associations, not causal effects. Family vulnerability strongly stratifies which young people sit in the lower tail of the depression-related outcome distribution. The translational opportunity is early support, not causal attribution or parental blame.

Critically, changes in family circumstances explain only a small share of the overall rise in youth depression — but they powerfully identify which young people are being left behind within it. That is exactly the evidence profile that supports earlier identification and better service planning, not parental blame.

The approach

Three linked work packages take FAMILY from evidence to implementation.

FAMILY combines evidence and data feasibility, safe-use co-design, and implementation readiness. The funded product is a co-designed Family-Aware Youth Depression Support Framework. In concrete terms: a small set of evidence-graded family-context domains, safe-use principles with real intake and assessment wording, explicit do-not-infer rules, escalation and safety protocols, and age-stratified use cases — paired with a national linked-data specification so the next-stage validation study can start the day this one ends.

HILDA provides the proof-of-concept marker lab, PLIDA provides the national administrative feasibility spine, and co-design provides the safety and implementation engine. NSW/CHeReL/education data provide a future scale-up pathway, not the core two-year dependency.

WP1 · Evidence & data architecture

HILDA marker development as the analytic laboratory, triangulated with a PLIDA administrative spine — Core Relationships, National Health Survey, National Survey of Mental Health and Wellbeing, MBS/PBS and socioeconomic modules.

WP2 · Safe-use co-design

Young people, carers, clinicians, primary-care and youth-service providers, and data-governance experts co-design safe-use principles and "do not infer" rules for family context.

WP3 · Implementation & scale-up

Partner-tested vignettes and workflows anchored in adolescent and young-adult primary care. Youth mental-health intake is the second tested use case. School wellbeing and community mental health are framework use cases and future scale-up settings.

In analytic terms, the empirical component asks whether parent- and household-level markers — such as parental depression, service contact, socioeconomic stress, household structure and related vulnerabilities or protective factors — predict youth depression-related outcomes, including psychological distress, clinical/survey indicators, treatment contact, service intensity and care gaps. The goal is observational marker development and service translation, not causal attribution.

PLIDA's Core Relationships module is the key administrative opportunity, providing parent-child and partner relationships where available, triangulated with the National Health Survey, National Survey of Mental Health and Wellbeing, MBS, PBS, income, demographic, location, Census and social-service modules. The project will not overclaim diagnostic precision: survey-based clinical indicators, self-reported measures, and administrative treatment/service-contact proxies will be clearly distinguished.

What FAMILY will never do

Partner value

What partners help shape, and what they receive in return.

FAMILY is a co-designed translational project, not a one-way academic exercise. Partners help decide which family-context markers are used and what must never be inferred. They gain acknowledgement, practical outputs and a foothold in youth depression policy.

For potential implementation partners

FAMILY is seeking a primary-care or youth-service implementation partner to provide modest in-kind support. This would usually mean a letter of support and staff time to advise on adolescent primary-care or youth-service workflows, review vignettes, and help test whether the family-aware framework is practical, safe and usable in real service settings.

A generic letter-of-support template is available for partners to adapt. The template is not a commitment and should be edited by the partner organisation to reflect what it can realistically provide, including the authorised officer, lead contact, in-kind contribution and estimated value.

Download generic partner letter template

Who we are seeking

A compact, complementary team — not a large consortium.

The immediate need is a small set of collaborators who can make the framework clinically valid, youth-safe, implementable and data-feasible. Roles can cover clinical input, lived-experience governance, implementation testing or data governance.

Youth Depression Clinical Lead

Child/adolescent psychiatry, clinical psychology, adolescent medicine or youth mental-health care. Owns clinical validity, outcome interpretation, safety and escalation.

Lived-Experience & Co-design Organisation

Youth depression lived and living experience, carers, family safety and trauma-informed co-design. Embedded in governance and design, not advisory decoration.

Primary Care / Youth Service Implementation Partner

Adolescent or young-adult primary care, youth health or youth mental-health intake. Grounds the framework in real workflows, referrals and staffing realities.

PLIDA / Data Governance

PLIDA/DataLab, Core Relationships, linked survey modules, depression-related service outcomes, privacy, disclosure control and data governance expertise.

Later scale-up: education-sector and NSW linked-data advisers welcome.

Research team

Chief Investigators and Associate Investigators spanning quantitative methods, clinical psychology, adolescent health, education and justice health.

FAMILY brings together expertise in intergenerational quantitative methods, clinical and developmental psychology, adolescent primary care, educational psychology, and linked-data/justice-health outcomes. The team continues to seek lived-experience and service-implementation partners to strengthen the translational pathway.

Chief Investigators

Sergey Alexeev

University of Sydney · UNSW

Lead applicant · intergenerational quantitative methods, linked data, health economics

Anam Bilgrami

Macquarie University

Youth depression policy, preferences/evaluation, education-sector links

Jesse Young

University of Toronto · University of Melbourne

Psychiatric epidemiology, justice health, data-linkage methodology

Ania Samarawickrama Lucewicz

University of Sydney

General practitioner, FRACGP; adolescent primary care, linked health data, whole-of-family models of care.

Associate Investigators

Carly Johnco

Macquarie University

Clinical psychology, anxiety and related disorders across the lifespan; Deputy Director, Lifespan Health & Wellbeing Research Centre

Melissa Kang

University of Sydney

Adolescent health, primary care and youth-friendly health services

Frances Doyle

Macquarie University

Clinical psychology; early detection, prevention and treatment of youth depression

Viviana Wuthrich

Macquarie University

Clinical psychology, anxiety and depression across the lifespan; Director, Lifespan Health & Wellbeing Research Centre

Emma Burns

Macquarie University

Educational psychology; teacher-student relationships, adolescent motivation and wellbeing

The team continues to seek a primary care/youth-service implementation partner, a lived-experience/co-design partner, and PLIDA/data-governance expertise to strengthen the implementation and scale-up pathway.

Interested in partnering?

FAMILY is being developed for the 2026 MRFF Million Minds Mental Health Research Mission, Stream 1 Incubator (Topic C). If FAMILY is relevant to your organisation's priorities — clinical, implementation, lived-experience, or data governance — we would welcome an initial conversation. The project spine is an early four-page document; the 2026 proposal is a working draft and will continue to change as the MRFF submission develops.

We are finalising the investigator team and partner letters by early August 2026, ahead of the MRFF submission closing 16 September 2026. If FAMILY fits your organisation, now is the moment.