2026 MRFF Million Minds Mental Health Research Mission · Stream 1 Incubator · Topic C · In development
Safe family-aware early identification and service planning for youth depression
A two-year translational incubator that develops and de-risks a safe, family-aware framework for identifying and supporting youth depression. HILDA provides the proof-of-concept marker lab, PLIDA provides the national administrative feasibility spine, co-design provides the safety and implementation engine, and NSW/CHeReL/education data provide a future scale-up pathway — not the core two-year dependency.
The project spine is an early four-page document for discussion. A full MRFF proposal is in development and will be linked here once drafted.
The problem
The practical gap is not simply that we need a larger dataset. It is that services and policy lack an evidence-based, youth-safe way to use family context in early identification and service planning. FAMILY asks which family-context markers are evidence-supported, administratively measurable, clinically useful, acceptable to young people and carers, and safe enough to inform support.
Preliminary HILDA work provides proof of concept: a data-efficient intergenerational sample of 43,817 parent-child pairs across 23 waves shows significant maternal mental-health gradients for both sons and daughters, with near-zero paternal estimates in the same model. The follow-up youth mental-health analysis is deliberately cautious — it shows family vulnerability strongly stratifies which young people sit in the lower tail of the mental-health distribution, without claiming causal parental effects or parental blame. The translational opportunity is early support, not causal attribution.
The approach
FAMILY is architected as evidence and data feasibility, safe-use co-design, and implementation readiness — with NSW/CHeReL/education data treated as a future scale-up pathway rather than a core two-year dependency. The funded product is not more HILDA regressions and not a bespoke NSW linkage that must complete inside 24 months. It is a co-designed Family-Aware Youth Depression Support Framework.
WP1 · Evidence & data architecture
HILDA marker development as the analytic laboratory, triangulated with a PLIDA administrative spine — Core Relationships, National Health Survey, National Survey of Mental Health and Wellbeing, MBS/PBS and socioeconomic modules.
WP2 · Safe-use co-design
Young people, carers, clinicians, primary-care and youth-service providers, and data-governance experts co-design safe-use principles and "do not infer" rules for family context.
WP3 · Implementation & scale-up
Partner-tested vignettes and workflows for GP, youth mental-health intake, school wellbeing and community mental-health settings, plus a NSW/CHeReL/education extension plan for future validation.
In analytic terms, the empirical component asks whether parent- and household-level markers — such as parental mental health, service contact, socioeconomic stress, household structure and related vulnerabilities or protective factors — predict youth depression-related outcomes, including psychological distress, clinical/survey indicators, treatment contact, service intensity and care gaps. The goal is observational marker development and service translation, not causal attribution.
PLIDA's Core Relationships module is the key administrative opportunity, providing parent-child and partner relationships where available, triangulated with the National Health Survey, National Survey of Mental Health and Wellbeing, MBS, PBS, income, demographic, location, Census and social-service modules. The project will not overclaim diagnostic precision: survey-based clinical indicators, self-reported measures, and administrative treatment/service-contact proxies will be clearly distinguished.
Partner value
FAMILY is structured as a co-designed translational project, not a one-way academic exercise. Partners help decide which family-context markers are used, how they are used, and what should never be inferred — and gain acknowledgement, translational outputs, and a foothold in a fast-developing area of youth mental-health policy.
Who we are seeking
The immediate need is a small set of collaborators who can make the family-aware framework clinically valid, youth-safe, implementable and data-feasible. Roles can be tailored around clinical input, implementation testing, lived-experience governance, data governance, or education-sector scale-up.
Youth Depression Clinician
Child/adolescent psychiatry, clinical psychology, adolescent medicine or youth mental health. Owns clinical validity, outcome interpretation, safety and escalation.
Primary Care / Youth Service Implementation
GP, headspace-style service, youth health, community mental health or stepped-care setting. Grounds the framework in real workflows, referral and staffing realities.
Lived-Experience & Co-design
Youth depression lived/living experience, carers, family safety and trauma-informed co-design. Embedded in governance and design, not advisory decoration.
PLIDA / Data Governance
PLIDA/DataLab, Core Relationships, linked survey modules, mental-health service outcomes, privacy, disclosure control and data governance expertise.
Education & NSW Extension
Whether historical Tell Them From Me and/or NSW Public Schools Surveys can support future scale-up; SERAP and custodian engagement pathways.
Not sure where you fit?
Get in touch and we will send the brief most relevant to your organisation's mandate — clinical leadership, co-design infrastructure, implementation expertise, or a service-translation pathway.
Research team
FAMILY brings together expertise in intergenerational quantitative methods, clinical and developmental psychology, adolescent primary care, educational psychology, and linked-data/justice-health outcomes. The team continues to seek lived-experience and service-implementation partners to strengthen the translational pathway.
Chief Investigator
Sergey Alexeev
University of Sydney · UNSW
Lead applicant · intergenerational quantitative methods, linked data, health economics
Associate Investigators
Anam Bilgrami
Macquarie University
Youth mental-health policy, preferences/evaluation, education-sector links
Jesse Young
University of Melbourne
Psychiatric epidemiology, justice health, data-linkage methodology
Ania Sams
University of Sydney
Faculty of Medicine and Health
Carly Johnco
Macquarie University
Clinical psychology, anxiety and related disorders across the lifespan; Deputy Director, Lifespan Health & Wellbeing Research Centre
Melissa Kang
University of Sydney
Adolescent health, primary care and youth-friendly health services
Frances Doyle
Macquarie University
Clinical psychology; early detection, prevention and treatment of youth mental-health problems
Viviana Wuthrich
Macquarie University
Clinical psychology, anxiety and depression across the lifespan; Director, Lifespan Health & Wellbeing Research Centre
Emma Burns
Macquarie University
Educational psychology; teacher-student relationships, adolescent motivation and wellbeing
The team continues to seek a primary care/youth-service implementation partner, a lived-experience/co-design partner, and PLIDA/data-governance expertise to strengthen the implementation and scale-up pathway.
FAMILY is being developed for the 2026 MRFF Million Minds Mental Health Research Mission, Stream 1 Incubator (Topic C). If FAMILY is relevant to your organisation's priorities — clinical, implementation, lived-experience, or data governance — we would welcome an initial conversation. The project spine is an early four-page document; a full proposal draft will be linked here as it develops.