2026 MRFF Million Minds Mental Health Research Mission · Stream 1 Incubator · Topic C · In development

FAMILY

Safe family-aware early identification and service planning for youth depression

A two-year translational incubator that develops and de-risks a safe, family-aware framework for identifying and supporting youth depression. HILDA provides the proof-of-concept marker lab, PLIDA provides the national administrative feasibility spine, co-design provides the safety and implementation engine, and NSW/CHeReL/education data provide a future scale-up pathway — not the core two-year dependency.

Get in touch Project spine ↗

The project spine is an early four-page document for discussion. A full MRFF proposal is in development and will be linked here once drafted.

43,817 parent-child pairs in the intergenerational HILDA proof-of-concept sample
23 HILDA waves underpinning the marker-development analysis
0–25 age range of young people in scope
2 yrs translational incubator timeframe, with no bespoke linkage dependency

The problem

Services lack an evidence-based, safe way to use family context in youth depression care.

Young people are embedded in families and households. Parental mental health, household shocks, family resources, service contact, economic stress, housing instability, relationship transitions and protective supports can all shape vulnerability, recognition, access to care, persistence and recovery. Yet most evidence and service responses still start and end with the individual young person.

The practical gap is not simply that we need a larger dataset. It is that services and policy lack an evidence-based, youth-safe way to use family context in early identification and service planning. FAMILY asks which family-context markers are evidence-supported, administratively measurable, clinically useful, acceptable to young people and carers, and safe enough to inform support.

Preliminary HILDA work provides proof of concept: a data-efficient intergenerational sample of 43,817 parent-child pairs across 23 waves shows significant maternal mental-health gradients for both sons and daughters, with near-zero paternal estimates in the same model. The follow-up youth mental-health analysis is deliberately cautious — it shows family vulnerability strongly stratifies which young people sit in the lower tail of the mental-health distribution, without claiming causal parental effects or parental blame. The translational opportunity is early support, not causal attribution.

The approach

Three work packages, not four equal studies.

FAMILY is architected as evidence and data feasibility, safe-use co-design, and implementation readiness — with NSW/CHeReL/education data treated as a future scale-up pathway rather than a core two-year dependency. The funded product is not more HILDA regressions and not a bespoke NSW linkage that must complete inside 24 months. It is a co-designed Family-Aware Youth Depression Support Framework.

WP1 · Evidence & data architecture

HILDA marker development as the analytic laboratory, triangulated with a PLIDA administrative spine — Core Relationships, National Health Survey, National Survey of Mental Health and Wellbeing, MBS/PBS and socioeconomic modules.

WP2 · Safe-use co-design

Young people, carers, clinicians, primary-care and youth-service providers, and data-governance experts co-design safe-use principles and "do not infer" rules for family context.

WP3 · Implementation & scale-up

Partner-tested vignettes and workflows for GP, youth mental-health intake, school wellbeing and community mental-health settings, plus a NSW/CHeReL/education extension plan for future validation.

In analytic terms, the empirical component asks whether parent- and household-level markers — such as parental mental health, service contact, socioeconomic stress, household structure and related vulnerabilities or protective factors — predict youth depression-related outcomes, including psychological distress, clinical/survey indicators, treatment contact, service intensity and care gaps. The goal is observational marker development and service translation, not causal attribution.

PLIDA's Core Relationships module is the key administrative opportunity, providing parent-child and partner relationships where available, triangulated with the National Health Survey, National Survey of Mental Health and Wellbeing, MBS, PBS, income, demographic, location, Census and social-service modules. The project will not overclaim diagnostic precision: survey-based clinical indicators, self-reported measures, and administrative treatment/service-contact proxies will be clearly distinguished.

Partner value

What partners help shape, and what they receive in return.

FAMILY is structured as a co-designed translational project, not a one-way academic exercise. Partners help decide which family-context markers are used, how they are used, and what should never be inferred — and gain acknowledgement, translational outputs, and a foothold in a fast-developing area of youth mental-health policy.

Who we are seeking

A compact, complementary team — not a large consortium.

The immediate need is a small set of collaborators who can make the family-aware framework clinically valid, youth-safe, implementable and data-feasible. Roles can be tailored around clinical input, implementation testing, lived-experience governance, data governance, or education-sector scale-up.

Youth Depression Clinician

Child/adolescent psychiatry, clinical psychology, adolescent medicine or youth mental health. Owns clinical validity, outcome interpretation, safety and escalation.

Primary Care / Youth Service Implementation

GP, headspace-style service, youth health, community mental health or stepped-care setting. Grounds the framework in real workflows, referral and staffing realities.

Lived-Experience & Co-design

Youth depression lived/living experience, carers, family safety and trauma-informed co-design. Embedded in governance and design, not advisory decoration.

PLIDA / Data Governance

PLIDA/DataLab, Core Relationships, linked survey modules, mental-health service outcomes, privacy, disclosure control and data governance expertise.

Education & NSW Extension

Whether historical Tell Them From Me and/or NSW Public Schools Surveys can support future scale-up; SERAP and custodian engagement pathways.

Not sure where you fit?

Get in touch and we will send the brief most relevant to your organisation's mandate — clinical leadership, co-design infrastructure, implementation expertise, or a service-translation pathway.

Research team

A Chief Investigator and Associate Investigators spanning clinical psychology, adolescent health, education and justice health.

FAMILY brings together expertise in intergenerational quantitative methods, clinical and developmental psychology, adolescent primary care, educational psychology, and linked-data/justice-health outcomes. The team continues to seek lived-experience and service-implementation partners to strengthen the translational pathway.

Chief Investigator

Sergey Alexeev

University of Sydney · UNSW

Lead applicant · intergenerational quantitative methods, linked data, health economics

Associate Investigators

Anam Bilgrami

Macquarie University

Youth mental-health policy, preferences/evaluation, education-sector links

Jesse Young

University of Melbourne

Psychiatric epidemiology, justice health, data-linkage methodology

Ania Sams

University of Sydney

Faculty of Medicine and Health

Carly Johnco

Macquarie University

Clinical psychology, anxiety and related disorders across the lifespan; Deputy Director, Lifespan Health & Wellbeing Research Centre

Melissa Kang

University of Sydney

Adolescent health, primary care and youth-friendly health services

Frances Doyle

Macquarie University

Clinical psychology; early detection, prevention and treatment of youth mental-health problems

Viviana Wuthrich

Macquarie University

Clinical psychology, anxiety and depression across the lifespan; Director, Lifespan Health & Wellbeing Research Centre

Emma Burns

Macquarie University

Educational psychology; teacher-student relationships, adolescent motivation and wellbeing

The team continues to seek a primary care/youth-service implementation partner, a lived-experience/co-design partner, and PLIDA/data-governance expertise to strengthen the implementation and scale-up pathway.

Interested in partnering?

FAMILY is being developed for the 2026 MRFF Million Minds Mental Health Research Mission, Stream 1 Incubator (Topic C). If FAMILY is relevant to your organisation's priorities — clinical, implementation, lived-experience, or data governance — we would welcome an initial conversation. The project spine is an early four-page document; a full proposal draft will be linked here as it develops.